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Biology, 18.01.2021 22:00 jtbrown0093
This change in hydrogen bonding pattern is all the bacteria needs to survive. Interestingly changing an oxygen in vancomycin aglycone (compound 5 below) to an NH (compound 6 below) restores activity against VRE, strains with D-Ala-D-Lac, and compound 6 is still active against strains with (D-Ala-D-Ala). Why
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This change in hydrogen bonding pattern is all the bacteria needs to survive. Interestingly changing...
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