Many genetic diseases result from the production of enzymes that are not shaped correctly. how does changing in an enzyme shape cause it to work poorly or not at all ?

i think that c)gold was found there

but i am not sure

"menstrual cycle is a complex cycle that consists of several processes. order of occurrence of steps in menstrual cycle are as follows:

1. high progesterone levels maintain the endometrium lining of the uterus.

2. endometrium lining breaks down and low levels of estrogen stimulate the pituitary to release fsh and lh.

3. fsh and lh stimulates the follicles to develop and the oocyte to produce estrogen.

4. rising estrogen levels suppress fsh production and development of other follicles.

5. a spike in lh causes follicle to rupture.

6. a breakdown of corpus luteum causes progesterone level to drop."