What is the best way to describe our current understanding of the one-gene/one-polypeptide hypothesis

It applies to prokaryotes but not to eukaryotes.

Explanation:

one-gene/one-polypeptide hypothesis is based on the idea that there is a structurally complex gene whereby each gene encodes a single polypeptide, that either operates on its own or under a relatively more complex protein.

However, based on the existing findings and research, the one-gene/one-polypeptide hypothesis "applies to prokaryotes but not to eukaryotes."

This is because one gene/one-polypeptide cannot be used to explain different spliced versions found in several eukaryote organisms

your answer is "the 1950's"

ya the other dude is right