A)Using an example explain how enzyme and habitation exploited to control human diseases B)Explain why the drug is poisonous to the Target organism but not to humans

A. Rifampicin is an example of an enzyme inhibiting drug, since it acts on the bacterial RNA polymerase, preventing the transcription and synthesis of proteins, so the bacteria is not viable and a human disease is controlled.

B. The drugs have specificity by microorganisms —target organisms— which are also smaller and more susceptible, while their effect is minimal or null in human cells and are not poisonous for them.

Explanation:

Bacteria, viruses, parasites and pathogenic fungi are microorganisms capable of producing disease in humans. One of the ways to fight infectious diseases is the use of drugs called antibiotics, capable of interfering with the development of microorganisms.

Antibiotics or antibacterials are capable of preventing the synthesis of the bacterial wall or its reproduction, intervening in the synthesis of proteins. They do this through enzymatic inhibition of these processes.

step 1: initiation

initiation is the beginning of transcription. it occurs when the enzyme rna polymerase binds to a region of a gene called the promoter. this signals the dna to unwind so the enzyme can ‘‘read’’ the bases in one of the dna strands. the enzyme is now ready to make a strand of mrna with a complementary sequence of bases.

step 2: elongation

elongation is the addition of nucleotides to the mrna strand. rna polymerase reads the unwound dna strand and builds the mrna molecule, using complementary base pairs. there is a brief time during this process when the newly formed rna is bound to the unwound dna. during this process, an adenine (a) in the dna binds to an uracil (u) in the rna.

step 3: termination

termination is the ending of transcription, and occurs when rna polymerase crosses a stop (termination) sequence in the gene. the mrna strand is complete, and it detaches from dna.