Biology, 20.11.2020 07:00 lilyplant4289
Nuclear hormone receptors form a complex with their ligands, other proteins, and DNA control elements in order to regulate the expression of specific genes. These nuclear hormone receptors have four principal domains. Categorize each trait according to the appropriate nuclear hormone receptor domain with which it is associated.
Domains:
amino-terminal activation domain
DNA binding domain
hinge domain
ligand-binding domain
Traits:
1) binds coactivators
2) carboxyl-terminal end
3 )center of receptor
4) 9 conserved cysteine residues
5) zinc-finger domain
6) nuclear localization signal
7) AF2 activation domain
8) steroid-binding hydrophobic pocket
9) binding of corepressor proteins
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