What happens to a liquid when you keep on cooling it until it changes?

THE LIQUID FREEZES

Explanation:

It turns into a solid because it gets very cold.

an active site is a region that is present on an enzyme where the reactants or the substrate molecules we can say bind and experience a chemical reaction. the substrate is basically a reactant whose concentration is changing and that is converting into a product after binding at the active site of an enzyme

there are so many examples for that in different areas, like biology experiment carried out in our lab recently.

here's one link: