Amyloid fibrils are associated with many fatal degenerative diseases of humans and livestock. Livestock diseases such as scrapie in sheep and bovine spongiform encephalitis (BSE, or mad cow disease) have major negative impacts on agriculture. Human diseases characterized by amyloid fibrils include Alzheimer's disease and Creutzfeldt-Jakob disease. Choose the true statements about amyloid fibrils.

a. Amyloid fibrils have a high amount of β-sheet structure.
b. Proteins that convert to an amyloid structure form soluble fibrils.
c. Because most newly synthesized proteins fold correctly, the accumulation of misfolded proteins (or fragments) tends to occur slowly, thus explaining the slow onset of disease.
d. An amyloid fibril is stabilized by hydrogen bonds between small hydrophilic residues.
e. Proteins that form amyloid fibrils are normally soluble.

a. Amyloid fibrils have a high amount of β-sheet structure.

c. Because most newly synthesized proteins fold correctly, the accumulation of misfolded proteins (or fragments) tends to occur slowly, thus explaining the slow onset of disease.

e. Proteins that form amyloid fibrils are normally soluble.

Explanation:

Amyloids can be defined as fibrillar protein aggregates composed of a β-sheet secondary structure. In general, the amyloid fibrils are composed by soluble proteins that are assembled to form insoluble resistant to degradation fibers. In humans, defective amyloid proteins produced by misfolding are known to produce diseases (amyloidosis) capable of altering the function of tissues and organs. Systemic forms of amyloidosis are common in neurodegenerative disorders.

hey bro i looked it up on google the structure of the eye-spot in euglena viridie, e. ehrenbergii, and phacus pyriyorme is not as franzé haa described it. the so-called “crystal body” and “lens bodies” were not found in any of the individuals of the species examined by me. as earlier observers have stated, the eye-spot consists simply of a mass of pigment granules arranged in a single layer, and probably embedded in a protoplasmic framework, but the latter could not be seen, and its presence was only inferred from the fact that the pigment granules must be held together in some way, thd the eye-spot as a whole is capable of expansion, and that the pigment granules can be separated from each other.

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