What are three different defects that could be responsible for malfunctioning lysosomes?

select the three correct answers.

a) a defect in the synthesis of the glucose-6-phosphate dehydrogenase

b) a defect in the mannose-6-phosphate receptor in the golgi apparatus

c) a defect in the releasing small molecules from digested materials into the cytosol

d) a defect in a hydrolytic enzyme that breaks down polysaccharide

e) a defect in the process of adding a mannose-6-phosphate signal to lysosomal hydrolases

f) a defect in the mannose-6-phosphate receptor in the mitochondria