Consider a system in which low levels of protein "Q" triggers production of hormone A. The reaction of target cells of hormone A is to produce and release hormone B, which stimulates production of hormone C. In response to hormone C, the target cells up-regulate protein Q. In this scenario we see an example of .

Negative feedback

Explanation:

Negative feedback is produced when a mechanism is amplified through an inverse loop, which tends to reduce the fluctuations in the system. In this case, the negative feedback mechanism represents a homeostatic response of the body where the release of a target hormone (hormone C) decreases in response to the increase of a protein (protein Q) upstream in the signaling pathway. Therefore, in this scenario, it is expected that negative feedback causes a decrease in hormone function.

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