Emily and Zach are two students working in the lab to improve the stability and activity of the newly discovered transport protein BCM1 in eukaryotic cells. While introducing mutations into the protein sequence that were predicted to improve the stability and activity of BCM1 Zach convinced Emily to mutate some of the amino acids in the N-terminal signal peptide region of the protein sequence. Subsequently, they expressed this mutated BCM1 protein in eukaryotic cells and observed very little transport across the membrane via the mutate BCM1 transporter in comparison to the levels of transport that was observed via the unmutated BCM1 transporter. Upon further analysis Emily determined that the reduction in transport across the mutated BCM1 transporter was due to mutations made in the signal peptide region of the BCM1 sequence. Explain to Zach the importance of this signal peptide region and disrupting it would lead to reductions in the BCM1 transporter activity.