Biology, 07.06.2020 04:01 janahiac09

At the molecular level, gene duplication often produces novelty in a lineage. This process provides another evolutionary pathway by which a protein can switch functions, without loss of the original function. What analytical approach helped the most to answer the question of evolution in the aldosterone-M receptor pair in the study of Jamie Bridgham and her colleagues

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Bridgham et al. (2006) showed that the interaction between a steroid hormone (aldosterone-M) and its receptor (mineralocorticoid) evolved by Darwinian gradualism. In this work, the authors demonstrated a primitive affinity between the hormone and its receptor that was initially present in chemically similar but more ancient ligands. This result has implications in understanding the association between gene duplication and the evolution of hormone signaling pathways. For example, in invertebrates, this work reinforces the importance of gene duplication in the existing interaction between paralogous glucocorticoid receptors and their receptor mineralocorticoid genes that were derived from duplication (Thornton 2001).

The publications above cited are the following:

J.T. Bridgham, S.M. Carroll, and J.W. Thornton (2006). Evolution of hormone-receptor complexity by molecular exploitation. Science, 312(5770), 97-101.

JW Thornton. Evolution of vertebrate steroid receptors from an ancestral estrogen receptor by ligand exploitation and serial genome expansions, Proc Natl Acad Sci USA (PNAS), 2001, vol. 98 10 (pg. 5671-5676).

Answer from: Quest

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hey, i believe your answer would be d. sugar ribose and the base uracil. i believe this is the answer, because rna consists of sugar ribose, adenine, guanine, cytosine, and uracil.

your first option is incorrect, because that's dna. where it consists of sugar deoxyribose, adenine, guanine, cytosine and thymine.

your second option is also incorrect, this is because sugar deoxyribose is in dna, and uracil is in rna. these two do not make sense together.

your third option being incorrect, because sugar ribose is in rna, but not the base of thymine. rna consists of uracil, not thymine.

lastly your fourth option being correct! this answer is correct, because both sugar ribose, and the base uracil are in rna! ~

answer is d. sugar ribose and the base uracil.

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At the molecular level, gene duplication often produces novelty in a lineage. This process provides...

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