How could large molecules cross the cell mebrane

When molecules are too large or too charged to cross the plasma membrane by diffusion or osmosis, there are other methods to accomplish their transport into or out of the cell. For example, some proteins in the plasma membrane are known as protein channels and they form a way for large or charged molecules to pass through the membrane.

Explanation:

americans began to notice growing differences between the northern and southern sections of the country. there were more people living in cities in the north, which made it more urban. more people lived on farms in the south, which made it more rural. while many people were farmers in the northern states, there were now other ways to make a living, such as working in mechanical cotton gins factories manufacturing cloth, tools and other goods. people in the north supported high tariffs on goods imported from europe because the extra cost encouraged people to “buy american” instead. in the southern states, planters did not like tariffs because they sold most of their production to europe and bought their tools from there as well. southerners believed the protective tariff was something that only northern factory owners keep their profits high. so the southern politicians came up with an idea. they would opt out. they would simply ignore the protective tariff. it was ‘null and void’ in south carolina. the state would not collect the taxes on goods imported into south carolina, no matter what the president said they had to do. this decision led to the nullification crisis.

sheep is a herbivore animal whereas grasshopper belongs to the class chordates but both of them feed on greens.  

if grasshopper and sheep feeding on a pasture land, i do not think both of them will have any impact on each other. however, the number of the species can make difference. since sheep feed on greens, there is a possibility there left no pasture land for the grasshoppers or they may get extinct.