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1. Gill filaments absorb oxygen from water and release carbon dioxide

2. Water is swallowed by the mouth and pumped to the gills

3. Water is pumped out behind the opreculum, or gill cover

Explanation:

Gills take oxygen out of the water and let water carry away carbon dioxide. Fish force water through their gills, where it flows past lots of tiny blood vessels. Oxygen seeps through the walls of those vessels into the blood, and carbon dioxide seeps out.

enzyme active site and substrate specificity

enzymes bind with chemical reactants called substrates. there may be one or more substrates for each type of enzyme, depending on the particular chemical reaction. in some reactions, a single-reactant substrate is broken down into multiple products