You have discovered an enzyme activated by PKC that modifies lipids. You call the enzyme Rafty and demonstrate that activated PKC directly phosphorylates Rafty, activating it to modify the plasma membrane lipids in the cell where PKC is active; these lipid modifications can be detected by dyes that bind to the modified lipids. Cells lacking Rafty do not have these modifications, even when PKC is active. What conditions would lead to signal-independent modification of the membrane lipids by Rafty?