Please help I have a lot more work to do

The engineering design process begins when?

A. a potential solution is evaluated
B. a problem is identified
C. a prototype is created
D. new uses for and old technology are discovered

Ineed to get this test done which of the following statements is correct in hour our immune system responds to a potential pathogen? a.) the skin will be the first line of defense, and then the many phagocytes in the bloodstream will attempt to consume the possible pathogen. b.) b cells will start reading the antigen code immediately and call t cells to assist in destroying the pathogen. c.) the adapted immune system will call on the innate immune system to destroy the pathogen. d.) the t-cells in the adapted immune systems are the first to recognize the pathogen