A 34-year-old woman with major depressive disorder comes
to the physician for a follow-up examination. She says that
her depressive symptoms are worsening. Multiple medication
regimens have been ineffective. The patient says that she
spoke recently with a former college roommate who also has
depression. Her friend is currently enrolled in a clinical trial
for a new antidepressant at a local center. The patient says,
"My friend seems to be doing really well with this new
medication, and I think I'd like to try it out to see if it would
work for me, too. Can you write me a referral to the center
where my friend is enrolled?" Which of the following is the
most appropriate initial response by the physician to this
patient's request?
(A) Decline to refer the patient because she has
treatment-refractory depression that
typically is not accepted into clinical trials
(B) Discuss the conduct of clinical trials so that the
patient has a clear understanding of how
they operate
(C) Inform the patient that she cannot receive future
care from the physician if she enrolls in the
clinical trial
(D) Inform the patient that she will not get the best
care possible if she enrolls in an
experimental trial
(E) Refer the patient to the center because so many
other treatment options have failed

B.Discuss the conduct of clinical trials so that the

patient has a clear understanding of how

they operate

Explanation:

Before the physician recommends their patient to a clinical trial, especially at the patient request, the doctor need to fully educate the patient about what is a clinical trial, and how do they select their subjects. The women and her friend may both have depression, but their status/severity may not be the same, therefore the patient may not be compatible with the trial her friend is partaking in.

prophase: we can observe the chromosomes to coil up and condense. they become visible. nuclear membrane and envelope disintigrate.s

metaphase: chromosomes align at the center, the metaphase plate. spindle fibers attach to centromeres of the sister chromatids. they meet at kinetochores.

anaphase: sister chromatids are pulled towards each opposing centromere, set on different poles.

telophase: chromosomes are now clustered up only on either sides of the cell. nuclear membranes reform, and a new cell wall forms along the cell plate. this will lead to cytokinesis, the process that divides the cell membrane and forms the cell wall.

image result for how many calories of energy will 20 grams of carbohydrates provide in one gram provides 4 calories

consuming the right balance of protein, carbohydrates and fat can you maintain a healthy weight and optimize your energy levels. protein and carbohydrates both contain 4 calories per gram, while fat provides 9 calories per gram.