What type of genetic mutation would cause the most dramatic change in the genetic make-up of an individual?

A base-pair substitution mutation where one base pair becomes another but codes for the same amino acid

A gene mutation that inserts one extra base pair into the genetic sequence

A single point mutation that changes the codon for a different amino acid

A mutation that deletes three consecutive base pairs from the genetic material

The gene mutation that inserts an extra base pair into the genetic sequence would cause the most dramatic change in the genetic make-up of and individual.

Explanation:

This is because the insertion of an extra base pair shifts the 3 base-pair sequences for amino acids. Each amino acid sequence after the the insertion has been changed. This means that each amino acid sequence codes for a different amino acid than originally intended, so the development of this person could be severely inhibited by their lack of the proper proteins.

B a gene mutation that inserts one extra base pair