Secreted proteins are synthesized in the cell then transported to the extracellular environment. Place the following cellular regions/compartments in order to correctly describe the path the protein would take from the beginning of synthesis to reaching its final destination outside the cell.
6 Extracellular matrix
2 Transport Vesicle
5 Cytoplasm
1 Rough Endoplasmic Reticulum
4 Transport Vesicle
3 Golgi Complex

1 Rough Endoplasmic Reticulum

2 Transport Vesicle

3 Golgi Complex

4 Transport Vesicle

5 Cytoplasm

6 Extracellular matrix

Explanation:

Rough endoplasmic reticulum is a organellle that produces proteins. The vesicles transport these proteins to the Golgi apparatus where they suffer different posttranslational modifications. Subsequently, the proteins are packed in vesicles and they transported in the cytoplasm to the extracellular matrix