Dominant and recessive alleles Choose true or false for each statement listed below. 1. The most prevalent alleles in a population are called wild type alleles. 2. Recessive alleles usually cause an increase in functional protein expression. 3. If a person is heterozygous for a recessive disease allele, they normally possess 50% of the normal amount of protein. 4. A single copy of an allele showing complete dominance typically masks the effects of a recessive allele. 5. Dominant alleles are always the result of gain of function mutations.

1 - true

2 - false

3 - true

4 - true

5 - false

Explanation:

The most prevalent alleles in a population are called wild type alleles. wild types alleles are also referred to as normal alleles while their alternate forms are the mutant alleles. Nomal alleles are always dominant in a population.

Recessive alleles usually cause an increase in functional protein expression. Recessive alleles cause a loss in protein functions and not increase its expression.

If a person is heterozygous for a recessive disease allele, they normally possess 50% of the normal amount of protein. Heterozygous individuals for a recessive allele have one normal allele and one abnormal allele. Hence, the protein expressing this gene will be 50% normal and 50% abnormal.

A single copy of an allele showing complete dominance typically masks the effects of a recessive allele. Dominant alleles usually masks the effect of recessive alleles when they are together.

Dominant alleles are always the result of gain of function mutations. While this may be true, it is not always the case in every situation.

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