Biology, 13.03.2020 03:36 jtal

In 1984, Martinez-Castro et al. (Cytogenetics and Cell Genetics 38:310-312) published a pedigree of a family in which two first cousins had married. They had six children three who were homozygous for t(13q;14q), two who were heterozygous for t(13q;14q), and one with a normal karyotype.

Should there be a lost fertility in the three homozygous t (13q:14q) offspring?
a. Yes
b. No

Calculate the probability of this particular outcome for this family (three translocation homozygotes, two translocation heterozygotes, and one normal karyotype). Assume that unbalanced gametes are viable.

a. 0.029
b. 0
c. 0.125
d. 0.500
e. 0.660
f. 0.059
g. 0.008
h. 1

Answers: 1

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In 1984, Martinez-Castro et al. (Cytogenetics and Cell Genetics 38:310-312) published a pedigree of...

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