How are histone modification enzymes (such as HATs) and chromatin remodeling complexes recruited to unmodified chromatin, and how are they thought to aid in the activation of transcription from previously silent genes?

A histone modification mechanism proliferate through a process that includes post translational modification procedure. The methylation, acetylation as well as ubiquitylation are one of the main modifiers that help in activation of silent genes and ultimately these covalently bonded histone modifiers help in regulating chromatin. The PTM has a main role in altering histone structure by these modifier's recruitment