DNA synthesis always takes place from the 5' to the 3' end. The template strands from dsDNA are aligned in opposite directions from each other. How does nature deal with this situation

Ras is a g-protein that is activated when a growth factor attaches to egfr. its activation results in the replacement of a gdp molecule with a gtp molecule, thus allowing a signal transduction pathway to be activated. considering the signal pathway illustrated on this page, what is one potential outcome of a mutation in the ras gene that leads to ras protein hyperactivity. be specific.