A negative feedback system .
a. accelerates changes in body function
b. takes place solely in the brain
c. is responsible for the regulation of body temperature
d. mostly occurs in the action of skeletal muscles
e. is caused by the presence of fever in humans

c. is responsible for the regulation of body temperature

Explanation: Negative feed back system is a reaction that occur in a system leading to a decrease in function. It occur as a response to stimulus and it could be the evaluation of an happening or occurrence.

Biological negative system include

Regulation of body temperature by the hypothalamus after receiving signals. If the temperature is too high the body sweat to reduce the heat and when its cold the body shiver to increase the temperature.

Blood pressure regulation is also a Biological negative feedback. When the pressure is increased signals are been sent to heart by the brain to slow the rate of blood been pumped into the heart and the pressure is then regulated.

this protocol provides a detailed procedure for co-immunoprecipitation (co-ip) to identify protein–protein interactions.