Peter and Victoria are both carriers of a serious autosomal recessive disorder that is lethal in early childhood. They want to have a child who is healthy so they have a preimplantation genetic diagnosis. The test shows that their child will not have the disease, but when she is born it turns out she does have the disease. What could have happened in this situation?

a. The cell that was tested in the preimplantation genetic diagnosis had a mutation causing it to be different from the rest of the cells in the embryo.
b. The embryo mutated during development from the initial time of the testing to develop the disease.
c. The preimplantation genetic diagnosis is only accurate for non-lethal diseases.
d. Either Peter or Victoria is actually homozygous recessive.

Option (a).

Explanation:

The autosomal recessive disorder is the disorder that are visible in the homozygous recessive condition only. The traits might be inherited in nature.

The screening of this test can be done by the genetic diagnosis at fetal level. Although, the test showed that the child is normal but she shows the disease that might occur due tom the mutation in the cells that cannot be diagnosed during genetic screening. This might occur probably due to the spontaneous mutation and occur rarely at the time of testing.

Thus, the correct answer is option (a).

the overall balanced equation

6co2 + 6h2o > c6h12o6 + 6o2

sunlight energy

where: co2 = carbon dioxide

h2o = water

light energy is required

c6h12o6 = glucose

o2 = oxygen

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