Other things being equal, what is a potential disadvantage of an enzyme having a very high affinity for its substrate?

anti-human il13 stable cell line (lebrikizumab) can be provided from creative biolabs.

explanation:

that would be called plucking : )

explanation:

''plucking, also referred to as quarrying, is a glacial phenomenon that is responsible for the erosion and transportation of individual pieces of bedrock, especially large "joint blocks". as a glacier moves down a valley, friction causes the basal ice of the glacier to melt and infiltrate joints (cracks) in the bedrock."

where in your body is there an enzyme that does function at a high or low ph? what is the name of that enzyme and its function?