Need help ASAP.
For biology

(1.)Which question below do scientists need to answer, to determine whether CRISPR can be used to fight a new bacterium that is resistant to antibiotics? (Circle all that apply)
A. Where did the bacterium come from?
B. What sequence of nucleotides does the guide RNA need to include, to kill the bacterium?
C. What proteins do the virus’s guide RNA code for?

(2.) Which of the following system components is likely to be direct (immediate) cause the antibiotic-resistant bacterium’s own DNA to be destroyed?
A. the invasion of the bacteriophage (virus) into the bacterium
B. the action of the Cas-9 protein
C. the production of the Cas-9 protein
D. the coding of the guide RNA