Arrange the events of synaptic transmission in correct sequence. (1) sodium ions diffuse into the cell and cause a local potential (2) neurotransmitter binds with receptor on postsynaptic cell (3) neurotransmitter diffuses across the synaptic cleft (4) membrane permeability to sodium ions on postsynaptic cell increases (5) action potential A. 5, 2, 3, 4, 1 B. 5, 2, 3, 1, 4 C. 5, 3, 4, 1, 2 D. 5, 4, 3, 2, 1 E. 5, 3, 2, 4, 1

Arrange the events of synaptic transmission in correct sequence

(1) sodium ions diffuse into the cell and cause a local potential

(2) neurotransmitter binds with receptor on postsynaptic cell

(3) neurotransmitter diffuses across the synaptic cleft

(4) membrane permeability to sodium ions on postsynaptic cell increases

(5) action potential causes release of neurotransmitter

5,3,2,4,1

Explanation:

The firing of an action potential at pre-synaptic neuron makes its axon terminal to release the neurotransmitters in the synaptic cleft. The released neurotransmitter molecules then bind to their receptors present at the surface of the dendrites of the postsynaptic neuron. This binding opens ion channels and allows the specific ions to enter into the postsynaptic neuron. The opening of Na+ channels allows these ions to enter into the neuron and changes the membrane potential. This changed membrane potential is called local potential and is a depolarizing graded potential.

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