What role does nano liposome play in gene therapy? who can tell me detailed information? any would be appreciated. in advance!

The longer the gene vector circulates in the body, the easier it is for the target gene concentration of the target cell or target organ to reach the therapeutic concentration. The internal circulation time is directly related to the particle size of the carrier. Traditional liposomes and carriers with large particle diameters enter the systemic circulation and are affected by opsonin in the plasma. Liposome are cleared by the reticuloendothelial system in a short time, which affects gene transmission and therapeutic effects. nano liposome  have a smaller particle size, which can increase their circulation time in the body to a certain extent and enhance the role of their gene carriers.

Explanation:

https://www.creative-biostructure.com/nano-liposomes-formulation-production-617.htm

when a reversible reaction is occurring in both directions at the same rate; the products and reactants do not change in concentration. a chemical reaction where the compound is broken into its constituent parts.