If an elderly person has less protein in the blood than a younger person, how would you adjust the dose of a drug that has high protein binding?

The correct answer is - lower dose than person with more protein.

Explanation:

Drugs are work by binding with the protein to enable or inhibit the reaction or process on individual. Proteins that are present in the blood are that carry the receptors to bind such drug component.

A drug need higher dose if the drug has high affinity to bind to protein to express its role in the body. So, the elderly person with less protein need to less dose than the person with more protein.

Thus, the correct answer  lower dose than person with more protein.

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