Amedical researcher is trying to develop a diagnostic technique for a disease which is characterized by replication of a particular chromosomal region. what would be the most appropriate technique.

The correct answer is - FISH or fluorescence in situ hybridization.

Explanation:

Fluorescence in situ hybridization or FISH is a technique that used to help researchers to map and image the genetic material that is present in the cell of an individual. It uses the fluorescent probes that attached to part of the nucleic acid or the region of the chromosome with a high degree of complementarity.

It can be used for getting knowledge of abnormalities or mutations in the chromosomal region or genetic mutation. This molecular cytogenetic technology helped n the testing of if there are extra copies of the HER2 gene in the cells that are extracted from breast cancer biopsy.

Thus, the correct answer is - FISH or fluorescence in situ hybridization.