Efudex cream:
a) may be used as an anti-infective.
b) should be applied 3-4 times daily.
c) should be applied with gloves or a nonmetallic object.
d) is available as an otc product. answer with

C) Should be applied with gloves or a nonmetallic object.

Explanation:

Efudex is an antimetabolite cream used to treat the skin problem related to cancer that is basal cell cancer and actinic keratoses.  The cream works by inhibiting and death of the fast-growing cell in the skin and thus is antineoplastic in action.

The Efudex is a useful cream that should be used with the precautions and safety measures so it should be applied only 1- 2 times daily, should be used applied by wearing gloves or fingertips or non-metallic objects.

Since the efudex should be applied with non-metallic object or glove, therefore, Option-C is the correct answer.

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