In the meselson-stahl experiment, which mode of replication was eliminated based on data derived after one generation of replication

Conservative mode of replication

Explanation:

Meselson and Stahl performed the experiment to test how the DNA molecule replicates in the organisms.

He performed the experiment on E. coli by culturing them in N¹⁵ isotope and then transferring them to N¹⁴ isotope.

When he analysed the DNA sample through density centrifugation he found that in Generation One or one round of replication the intermediate band between the N¹⁴ isotope (lighter) and N¹⁵ isotope (heavier) isotopes.

This result showed that now the DNA contains both forms of isotope that is it is in favour of the semi-conservative and dispersive mode of replication but not conservative mode pf replication.

Thus, Conservative mode of replication is the correct answer.

the principles and empirical processes of discovery and demonstration considered characteristic of or necessary for scientific investigation, generally involving the observation of phenomena, the formulation of a hypothesis concerning the phenomena, experimentation to test the hypothesis, and development of a conclusion that confirms, rejects, or modifies the hypothesis.