Macrophages are . the best defense against parasitesb. cells that induce the lysis of virus-infected body cellsc. antigen-presenting cells that originate from neutrophilsd. large, phagocytic cells that can leave the circulation and enter the tissues of the bodye. short-lived cells that self-destruct soon after engulfing foreign invaders

D. large, phagocytic cells that can leave the circulation and enter the tissues of the body

Explanation:

Macrophagus are the type of white blood cells. These are responsible for providing immunity to the host against the pathogenic attack. These cells engulfs and digest the foreign agents like microbes, cellular debris, cancer cells and unwanted cellular components. This process is called as phagocytosis.

The monocytes transforms into macrophagus in conditions of infection and tissue damage. These monocytes leaves the blood stream and reach at the site of affected tissue or organ.