Inhibitors of the electron transport chain exert their effects through a variety of mechanisms.

a. rotenone rotenone atractyloside azide blocks electron transport and proton pumping via inhibition of complex iv.
b. azide rotenone atractyloside blocks electron transport and proton pumping via inhibition of complex i.
c. blocks electron transport and atp synthesis by inhibiting the exchange of atp and adp across the inner mitochondrial membrane.
d. blocks atp synthesis without inhibiting electron transport by dissipating the proton gradient.