The insulin receptor check all that apply. located at the cell surface __associated with the protein clathrin __ligand binding stimulates the activity of phospholipase c __a transmembrane protein __a dna-binding protein __located in the cell interior __receptor-ligand complex moves to the lysosome __receptor-ligand complex becomes concentrated in the nucleus __receptor activation can inhibit the synthesis of glycogen __the hormone-receptor complex activates specific gene transcription __internalization decreases the synthesis of cholesterol esters __action of this receptor diminishes the synthesis and activity of hmg-coa reductase__this receptor activates its own synthesis __biological activity of this receptor involves interaction with guanine nucleotide-binding proteins __this receptor has a protein kinase activity __not known to act through a second messenger