What follows are steps describing the series of reactions proposed to occur after the binding of a transcriptional activator to its response element on the dna. place them in the correct order.
(1) the chromatin remodeling complex binds to the core histones at the target region.
(2) the combined actions of the various molecular complexes increases promoter accessibility to the transcriptional machinery.
(3) the activator recruits a coactivator to a region of chromatin targeted for transcription.
(4) transcriptional machinery assembles at the site where transcription will be initiated.
(5) the coactivator acetylation the core histones of nearby nucleosomes.

Duchenne muscular dystrophy is a serious condition caused by a recessive allele of a gene on the human x chromosome. the patients have muscles that weaken over time because they have absent or decreased dystrophin, a muscle protein. they rarely live past their twenties. how likely is it for a woman to have this condition? a) women can never have this condition.b) one-fourth of the daughters of an affected man would have this condition.c) one-half of the daughters of an affected father and a carrier mother could have this condition.d) only if a woman is xxx could she have this condition.

The “ecological footprint” left by a citizen of a developed nation is about four times larger than that left by a citizen of a developing nation. why is this the case?

Astudy by solloch and et. al., in 2017, gives the map above which shows the frequency of alleles with a ccr5-delta32 mutations over 87 different countries. this mutation deletes the presence of a co-receptor (ccr5) on the outside of human t-cells (lymphocytes). some viruses, such as the one responsible for the black death and human immunodeficiency virus (hiv), require this receptor for attachment to host cells during the infection process. the black death was an epidemic that passed over northern europe during the 14th century killing nearly 60% of europeans. according to this information, which explanation best explains why northern europeans show a greater immunity for hiv than some other parts of the world?