subject
Biology, 26.11.2019 23:31 kaylaanndupree

You are interested in studying the secretion of the growth factor bdnf by neurons, and you want to track bdnf from its synthesis on ribosomes through secretion by cells. you hypothesize that (i) bdnf transits through the endomembrane system; (ii) is packaged into secretory vesicles and actively transported to the plasma membrane; and (iii) bdnf-containing vesicles fuse with the membrane when local ca2+ concentrations increase. propose an experiment that addresses each part of this hypothesis. in doing so, specifically state (i) the organelles of the endomembrane system that you would expect bdnf to travel through; (ii) the type of vesicle into which bdnf is packaged, as well as any motor protein(s) and/or cytoskeletal structures required to the bdnf-containing vesicle to the plasma membrane; and (iii) describe the ca2+-dependent mechanism through which you think vesicular fusion is regulated. for each part of the hypothesis, note two proteins that you might target (either by pharmacological or genetic approaches) to determine whether those processes are required for secretion of bdnf. state the expected outcome of your proposed experiment for each part of the hypothesis, based on targeting these proteins.

ansver
Answers: 1

Another question on Biology

question
Biology, 21.06.2019 14:50
Genetic diversity is the variation in the genes of an entire species. each circle represents a population of a particular species in different habitats. select the population with maximum genetic diversity
Answers: 1
question
Biology, 21.06.2019 20:00
Heyme with this one ❤ ☺❤ name the part of the cell concerned with the transmission of hereditary characters from parents to offspring. "i will mark brainlist "
Answers: 1
question
Biology, 21.06.2019 21:30
What was dr. willem johan kolff’s first step in using the scientific process to invent the hemodialysis machine? he built the machine and tried it with various patients, collecting data about its effectiveness. when a patient’s kidneys failed, he wondered if it would be possible to perform kidney functions with an external machine. he researched and collected data about numerous patients who exhibited symptoms of kidney failure. he drew conclusions from studies of various symptoms of kidney failure, and drew a design for the ideal external blood-processing machine.
Answers: 1
question
Biology, 21.06.2019 22:00
The earth consists of a variety of different organisms. despite their diversity, however, some similarities on the structural and metabolic levels may be seen. these similarities can be attributed to a. similarities among organisms in their proteins and nucleic acids. b. the ability of organisms to readily adapt to sudden environmental changes. c. similarities in organisms' habitats and niches. d. the ability of all organisms to interbreed and produce new species.
Answers: 1
You know the right answer?
You are interested in studying the secretion of the growth factor bdnf by neurons, and you want to t...
Questions
Questions on the website: 13722362