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Biology, 26.11.2019 19:31 Sushmitarai4934

One of the effector outcomes of tcr signaling in cd4+ t cells is t cell proliferation. your lab
discovered a new protein "g" in human cd4+ t cells. luckily, you also know the gene that
encodes protein g, so you can investigate its function by engineering a knockout of that gene
froin the cd4+ t cell. so you have generated two different phenotypes of same cd4+ t cell:
cd4+ t cells that express protein "g"0g cells) and cd4+ t cells that do not express protein
"g" (-g cells). you confirm that lack of“g” does not affect viability of the t cells. you
hypothesize that gis required for cd4+ t cell proliferation. you add an equal amount of each
cd4+ t cell type to separate culture dishes, activate and then count the number of cd4+ t
celis 72 hours later. how would you interpret the following results? (what would each
scenario tell you about your hypothesis?

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