Biology, 15.11.2019 01:31 Dracopaul03
In human genomes, the per nucleotide mutation rate is estimated to be about 2.5 x 10^-8. let us consider a recessive lethal genetic disease caused by a single point mutation. we will name the allele produced by this point mutation l, and the wild-type allele w. let us further assume that the disease phenotype expressed by ll individuals always kills those who have it before they reproduce. what would you predict the equilibrium frequency of the allele l be in the population after many generations? (you may assume hardy-weinberg equilibrium except for mutation and selection, and you may assume as an approximations that back-mutations from l to wild-type are rare enough to be ignored).
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In human genomes, the per nucleotide mutation rate is estimated to be about 2.5 x 10^-8. let us cons...
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