Which statement correctly explains how one of these regulatory molecules functions to regulate flow of matter through the glycolytic pathway?
a. when cellular citrate concentration is low as the result of low metabolic demand, citrate binds to and inhibits pfk to decrease flux through the pathway.
b. when cellular adp concentration is low as the result of high metabolic demand, adp binds to and activates pfk to increase flux through the pathway.
c. when cellular amp concentration is high as the result of high metabolic demand, amp binds to and inhibits pfk to decrease flux through the pathway.
d. when cellular citrate concentration is high as the result of low metabolic demand, citrate binds to and activates pfk to increase flux through the pathway.
e. when cellular atp concentration is high as the result of low metabolic demand, atp binds to and inhibits pfk to decrease flux through the pathway.

Bisphenol a (often called bpa) is a chemical found in products that people use every day, from water bottles to food containers to children's toys. unfortunately, bpa leaches out of its many products and makes its way into our bodies. what are the health effects of bpa exposure? ongoing research is finding that elevated exposure to bpa can affect a wide variety of developmental and physiological processes, but one of the first studies of bpa's health effects came about because of a simple mistake in the lab. at a laboratory at case western reserve university in 1998, geneticist patricia hunt was making a routine check of her female lab mice. as she extracted and examined developing eggs from the ovaries, she began to wonder what had gone wrong. she noticed that many of the eggs showed problems with their chromosomes, and some had irregular amounts of genetic material, which can lead to miscarriages and birth defects in mammals. she learned that a lab assistant had mistakenly washed the plastic mouse cages and water bottles with a harsh soap, releasing bpa from the plastic. knowing that bpa is an endocrine disruptor, a chemical that can enter organisms and mimic hormones, hunt set out to discover whether it had adversely affected her mice.