George beadle and edward tatum used mutant strains of neurospora to formulate the one-gene-one-enzyme hypothesis. researchers later updated this hypothesis to propose that one gene encodes one polypeptide because proteins can have multiple subunits. consider a heterodimeric protein. how many genes are required to form this protein?

(a) two
(b) four
(c) six
(d) three
(e) one

(A) two

Explanation:

A heterodimeric protein consists of two polypeptides (a polypeptide is a  chain of amino acids) that differ in amino acid composition, number or order in the chain sequence. Each polypeptide makes a different subunit of the protein.

One gene encodes one polypeptide, so if the protein has two different polypeptides, two genes are required to form this protein.

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