Movement of the chromosomes during anaphase of mitosis would be most affected by a drug that
a. reduces cyclin concentrations.
b. blocks astral microtubule formation.
c. prevents kinesin movement along microtubules.
d. prevents depolymerization of microtubules.
e. prevents attachment of the microtubules to the centromeres.

According to the extensive reading and research done on this pretty complex topic, the best answer to the question: Movement of the chromosomes during anaphase of mitosis would be most affected by a drug that:___,would be, D: prevented depolymerization of microtubules.

Explanation:

A lot of research has been done on how chromosomes move towards specific regions during mitosis and what forces prevent them from simply staying at one place, or rambling all over. Microtubulues, again, are the reason. Aside from the pretty complex machinery that forms during the stages of mitosis, research has shown that the reason why chromosomes will slide along the microtubules towards the pole is because of the interaction between the kinetochore (the site where the microtubule and chromosome plates assemble so that chromatids can be pulled towards where their new cell will be), and the polymerized or depolymerized microtubules. It is this depolymerization, basically the disassembly and reassembly of the tubules, that will further pull chromosomes towards their pole, more than motor proteins.