Apart of an mrna has the sequence ccg. which change to this sequence
would indicate a missense mutation?
uuu
ugu un
ugc cys
pro
messenger
second base in codon
rna codons uca
ucun
uau 1
uuc
ser
uua
uaa
uug
uag s
cuu
ccu
cau cgu
cuc
ccc
сас, cgc
cua
caau
cugi ccg cag) cgg
auu
aaut agu
auc) lle acc aac)
thr
aua aca aaa agai
augstart me acg aags
gcun
gaut ggu
guc gcc gac) ggo
gua gca
gga
gug)
gcg)
ggg!
cga
first base in codon
third base in codon
acu 1
fl•< • • < 020 cuplu cu
agc ser
aggi
guur
) ala

A single nucleotide changes in CCG which will result in missense mutation can be many possibilities.

Explanation:

Missense mutations  

CCG codes for Proline amino acid

•Mutation in first nucleotide codes for  

UCG specifically encodes Serine

ACG specifically encodes Threonine  

GCG specifically encodes Alanine                              

                                                                                      Missense mutation  

•Mutation in second nucleotide specify for coding

CUG specifically encodes Leucine

CAG specifically encodes Glutamine  

CGG specifically encodes Arginine

•Mutation in Third Nucleotide will not result in missense mutation because any point mutation in third nucleotide of codon will encode same amino acid i.e Proline.  

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