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Biology, 24.10.2019 18:43 tyrique86

You slowly develop eyelid drooping and muscle weakness. you go to the doctor and she believes you display classic symptoms of kss (kearns sayre syndrome), a mitochondrial disease. the doctor orders a test where a southern blot of your mitochondrial dna is performed using a blood sample. the southern blot shows one large band in the disease-negative control lane and a similar large band in your sample lane. the doctor is not convinced that the results rule out kss and orders more tests. why is the doctor not convinced that the results rule out kss?

a) the disease-negative control lane did not have the proper normal mitochondrial dna sample

b) a nonsynonymous or missense mutation may be present in the mitochondrial dna

c) your mitochondria may contain a nonsynonymous or missense mutation in the mitochondrial dna and another biopsy from a distinct site may show a different result

d) another biopsy from a distinct site may show a different result

e) two bands should have been present in the negative control sample

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