Which of the following statements regarding cyclin dependent kinase inhibitors is false? a. oncogenic signaling negatively regulates cdki’s. for example, akt signaling leads to cytoplasmic sequestration of cdki’s, and myc leads to transcriptional repression of cdki genes. b. some inhibitors are specific for the cyclin d: cdk4/6 complex. these inhibitors block progression past the r point. c. the cdki’s themselves are subject to positive regulation by cell stresses such as dna damage. d. some inhibitors are able to inactivate several cyclin: cdk complexes and therefore can promote cell cycle arrest at several checkpoints. e. all of the cdki’s have similar phosphatase activities.
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In a classic experiment using pea shape, mendel conducted two separate genetic crosses. in the first cross the parent plants were “true breeding” for pea shape; one had round peas ( r )and the other had wrinkled (r). the first cross produced a filial 1 generation of all round peas. in the second cross, mendel bred plants from the filial 1 generation. this cross produced different results. out of approximately 1000 plants, about 75% were round and 25% were wrinkled.
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Which of the following statements regarding cyclin dependent kinase inhibitors is false? a. oncogen...
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