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Biology, 16.10.2019 21:00 hrijaymadathil

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in cells, the primers for dna synthesis are short strands of rna, so each newly-synthesized strand of dna has a segment of rna at its 5' end. as replication proceeds, dna polymerases remove these rna segments and fill in the resulting gaps with dna. however, the gaps at the very 5' ends of the new strands cannot be filled in with dna. why not? dna replication leaves exposed about 100 nucleotides at the 5' end of each template strand, and these single-stranded ends are removed. what are the effects of this "end problem" on a cell's dna as it continues to divide?

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