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Suppose there is a mutation in a laminin-binding integrin gene that causes a loss of function in the cytoplasmic domains of the integrin. which of the following would you expect to observe as a result of this mutation?
(a)- the integrin would function normally because the cytoplasmic domain is not responsible for binding to laminin.
(b)- cell adhesion to laminin would decrease, but laminin-meditated gene expression would remain the same.
(c)- the strength of tissues would be decreased because the integrin could no longer associate with intermediate filaments in hemidesmosomes.
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