Which mutation is harmful to the organism?

a. a mutation allowing moths to camouflage better on blackened tree bark.

b. a mutation making staphylococcus aureus resistant to antibiotic methicillin.

c. a mutation inhibiting human immunodeficiency virus from attaching to and entering the cell.

d. a mutation causing uncontrolled cell division.

e. a mutation giving plant leaves a bitter taste to discourage herbivores from eating them.