Which atypical antipsychotics are approved for long-term use to prevent the recurrence of mood episodes in clients with bipolar disease? a. olanzapine b. quetiapine c. ziprasidone d. risperidone e. aripiprazole

The correct answers are option a. "Olanzapine", c. "Ziprasidone" and e. "Aripiprazole".

Explanation:

Olanzapine, Ziprasidone and Aripiprazole are three atypical antipsychotics with long-term use that proved that are able to prevent the recurrence of mood episodes in clients with bipolar disease. Olanzapine blocks the receptors for several neurotransmitters; Ziprasidone has a binding affinity for dopamine, serotonin, and histamine; while Aripiprazole enhance the dopaminergic activity by acting as a partial agonist at D2 receptors. This three antipsychotics work with different mechanisms of action and its use should be prescribed by a specialized that could determine which treatment could be more effective.

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