Rh factor is a gene with 2 alleles, rh positive, which is dominant to rh negative. the gene that codes for rh factor independently assorts from the abo gene. a female who has a blood and is rh positive (a positive) and whose mother is o negative marries a man that is o negative. what is the probability that they will have a child that is o positive?

1/4

Explanation:

The woman has an A blood type (she could be either AA or AO), but we know her mother had a type O blood, so she had two copies of the O allele. Therefore, the woman inherited one and her genotype for the ABO gene is AO.

The same thing can be said about the Rh gene. The woman is Rh+, so she could be either homozygous for the Rh+ allele or heterozygous. But because her mother was Rh negative, which is recessive, we know that she must have inherited a Rh- allele from her mother and is therefore Rh+ Rh-.

The man is O negative, so his genotype is completely recessive for both genes (OO Rh- Rh-).

If you do a Punnett Square to find out the possible genotypes of their offspring (please see attachment), you'll get that the probability of having an O positive child (OO Rh+_) is 1/4.

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